The small molecule phenamil induces osteoblast differentiation and mineralization. Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria. Clinical Performance of the Novel GenMark Dx ePlex Blood Culture ID Gram-Positive Panel. Comparison of 2 anal cytology protocols to predict high-grade anal intraepithelial neoplasia. Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells.

2020 Mar 7, Ashraf, A. P., Miyashita, K., Nakajima, K., Murakami, M., Hegele, R. A., Ploug, M., Fong, L. G., Young, S. G., Beigneux, A. P.> ;Journal of clinical lipidology. Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway. DYT1 Dystonia Patient-Derived Fibroblasts Have Increased Deformability and Susceptibility to Damage by Mechanical Forces.

He is experienced in general cardiology, valvular heart disease, and hyperlipidemia. Cell nuclei spin in the absence of lamin b1. Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome. Dr. Young is board certified in Cardiovascular Disease. He has been in practice for more than 20 years. Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a. GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism.

2020 Feb 9, Carroll, K. C., Reid, J. L., Thornberg, A., Whitfield, N. N., Trainor, D., Lewis, S., Wakefield, T., Davis, T. E., Church, K. G., Samuel, L., Mills, R., Jim, P., Young...> ;Journal of clinical microbiology. Stable isotope imaging of biological samples with high resolution secondary ion mass spectrometry and complementary techniques. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. 2018 Sep 28, Connect with other colleagues in the same hospital or clinic, Search all U.S. specialist profiles and refer a patient, Read the latest clinical news and earn CME/CEU credits. Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2. Genetic analyses of the role of RCE1 in RAS membrane association and transformation. Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling. 2020 Jan 17, Chen, N. Y., Yang, Y., Weston, T. A., Belling, J. N., Heizer, P., Tu, Y., Kim, P., Edillo, L., Jonas, S. J., Weiss, P. S., Fong, L. G., Young, S. G.> ;Proceedings of the National Academy of Sciences of the United States of America. Shop around, ask about cash discounts and consider community health centers and free clinics. AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase. Evolution and Medical Significance of LU Domain-Containing Proteins. An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner. Lipoprotein lipase is active as a monomer. Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase.

The coronavirus pandemic is adding an extra layer of complexity to the already confusing health care sign-up period. Dr. Stephen G. Young office is located at 650 Charles E Young Dr S, Los Angeles, CA. An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum. Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes. 2020 Jan 31, Heizer, P. J., Yang, Y., Tu, Y., Kim, P. H., Chen, N. Y., Hu, Y., Yoshinaga, Y., de Jong, P. J., Vergnes, L., Morales, J. E., Li, R. L., Jackson, N., Reue, K., Young, ...> ;Journal of lipid research. During his fellowship, Dr. Li received training in all areas of clinical endocrinology and continued to perform basic science research as a postdoctoral scholar in the lab of Dr. Stephen Young. 2019 Jul 12, Young, S. G., Fong, L. G., Beigneux, A. P., Allan, C. M., He, C., Jiang, H., Nakajima, K., Meiyappan, M., Birrane, G., Ploug, M.> ;Cell metabolism. As a Doximity member you'll join over a million verified healthcare professionals in a private, secure network. He joined the UCLA … Cardiologists diagnose and treat heart disease, such as congenital heart defects, coronary artery disease, heart rhythm disorders and heart failure. Lipoprotein size and susceptibility to atherosclerosis--insights from genetically modified mouse models. Factors Affecting the Prevalence of Strongly and Weakly Carcinogenic and Lower-Risk Human Papillomaviruses in Anal Specimens in a Cohort of Men Who Have Sex with Men (MSM). GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients. Disclaimer and a note about your health ». Hematologic effects of inactivating the Ras processing enzyme Rce1. Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis. He accepts multiple insurance plans. Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia. Slc25a17 Gene Trapped Mice: PMP34 Plays a Role in the Peroxisomal Degradation of Phytanic and Pristanic Acid. Rce1 deficiency accelerates the development of K-RAS-induced myeloproliferative disease. NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes. Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL. 2019 Dec 5, Gill, N. K., Ly, C., Kim, P. H., Saunders, C. A., Fong, L. G., Young, S. G., Luxton, G. W., Rowat, A. C.> ;Frontiers in cell and developmental biology. 2019 Jul 4, Leth, J. M., Leth-Espensen, K. Z., Kristensen, K. K., Kumari, A., Winther, A. L., Young, S. G., Ploug, M.> ;International journal of molecular sciences.

GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism. GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding.

Find your profile and take control of your online presence: Book an appointment with Dr. Joanna Ghobrial, Doximity / States / California / Los Angeles / Stephen Young, MD, Dr. Stephen Young, Dr. Stephen Young, MD, Dr. S Young, Dr. Stephen Granville Young. Acad. CD1d function is regulated by microsomal triglyceride transfer protein. See all conditions on Dr. Stephen G. Young's, Best Hospitals for Adult Cardiology & Heart Surgery, COVID-19 Complications: Registry Aims to Track Virus Impact on Heart. 2020 Apr 9, Jiang, H., He, C., Fong, L. G., Young, S. G.> ;Journal of lipid research. 2020 Apr 25, Van Veldhoven, P. P., de Schryver, E., Young, S. G., Zwijsen, A., Fransen, M., Espeel, M., Baes, M., Van Ael, E.> ;Frontiers in cell and developmental biology. Genetic and pharmacologic analyses of the role of Icmt in Ras membrane association and function. The posttranslational processing of prelamin A and disease. Prelamin A farnesylation and progeroid syndromes. Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression. He received his medical degree from Washington University School of Medicine in St. Louis and has been in practice 39 years.

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